Overbearingly arrogant, the other mages of the College both dislike and are highly suspicious of him. He, in turn, is highly suspicious of others (including the Dragonborn and Quaranir) and openly voices his belief that the mages of the College are inferior to those of the Thalmor. He also blames the Dragonborn's presence on the incompetence of the Arch-Mage. In conversation, Ancano will reveal that he is annoyed that he has not been called upon by the Arch-Mage for, "council." If asked, he also voices that the Thalmor are present in Skyrim to help with peace efforts, and this, "time of transition," for the Nords. If asked about his discussion with Mirabelle, Ancano reveals that he is angered by his "level of access" in the College.
Ancano has knowledge of the following spells:
During the College of Winterhold quest line, Ancano attempts to harness the energy of the Eye of Magnus, erecting a barrier between himself and other mages of the College; Savos Aren is killed in the process.
If the Dragonborn has not been given the Staff of Magnus quest and completed a few side quests, Ancano's barrier will become small. Ancano will also not harness the energy of the Eye of Magnus but instead walk around the Eye. The Dragonborn can interact with Ancano, but not while he is within the barrier.
Mirabelle has explained that members of the Synod recently visited the College, mentioning the Staff of Magnus. They were last known to be heading towards Mzulft; they may know more about where to find the staff.
The Dragonborn needs to retrieve the Staff of Magnus from within Labyrinthian and return with it to the College of Winterhold.
The Staff of Magnus has been recovered, and it is time to regain control over the College of Winterhold and strike down Ancano.
"Another new Apprentice, I see. Are you of the sort that believe you're here to change the world? Or are you only in it for yourself? I assure you that I'll be watching you -- all of you -- very closely."
- What is it you do here? "I am an advisor to the Arch-Mage. The Thalmor wish to promote relations with your College. I am at the Arch-Mage's disposal if he requires advice."
- Does the Arch-Mage often ask for advice? "Perhaps not as often as he should. In time, I believe he will be more trusting."
- I'd like to know more about the Thalmor. "Now that stability has been established between the Dominion and the Empire, we seek only to help Skyrim. To guide its people through this time of transition, to help lead them to a better future."
- What was that conversation with Mirabelle about? "Your superior and I were simply having a... discussion about my level of access to the College."
- It sounded more like an argument. "Well, perhaps that is why you're merely an Apprentice here."
- Is there a problem? "Nothing you need to concern yourself with. I shall be quite capable of observing everything that goes on here."
- It sounded more like an argument. "Well, perhaps that is why you're merely an Apprentice here."
- There's a rumor that you're spying for the Thalmor. "What? Preposterous, and just the sort of thing I would expect from mages who have nothing better to do with their time. I have made it quite clear that my only role here is as an advisor to the Arch-Mage. I would suggest that you not further spread this rumor."
(After talking to Urag gro-Shub about the missing books)
"You there. I have questions for you. You were in Saarthal, yes? It has come to my attention that something was found there."
- Maybe... "I know full well that you have. Please do not insult my intelligence. Tolfdir is still there now, is he? I shall expect a full report when he returns."
- Yes, we did. I just informed the Arch-Mage. "I am well aware. Tolfdir is still in Saarthal, is he? I shall be expecting a full report from him when he returns."
- How do you know anything about this? "It is my job to know these things. My role as advisor to the Arch-Mage is aided by knowing everything that transpires here."
- Why does this matter to you? "Something was discovered in Saarthal that was significant enough that Tolfdir sent a new member of the College, alone, to deliver word. That sounds precisely like the sort of thing that should matter to everyone. Especially me. Thank you for your help. You may go now."
"I need you to come with me immediately. Let's go."
- I don't understand what's going on. "Really? Well, allow me to clarify the situation. I'd like to know why there's someone claiming to be from the Psijic Order here in the College. More importantly, I'd like to know why he's asking for you specifically. So we're going to go have a little chat with him, and find out exactly what it is he wants."
- Why are you so concerned about this? "I'll be the one asking the questions. All you need to know is that the Psijic Order is a rogue organization, believing themselves to be above the law. They have clashed with the Aldmeri Dominion before, and I have no intention of allowing that to happen here."
- Aren't you just an advisor here? "Technically, that is true. But I still report to the Aldmeri Dominion, and I cannot ignore this situation. Don't worry, you can return to your petty squabbles and meaningless 'research' as soon as this matter is resolved."
(In front of the Arch-Mage's Quarters)
"Now, you are going to speak to this... Monk... and find out why he is here, and then he will be removed from College grounds."
- What do you want me to say to this monk? "Find out why he's here, and what he wants."
(After talking to Quaranir)
"I'm not sure what just happened but I assure you I will get to the bottom of it."
- Get to the bottom of what? "Whatever it is those Psijics are up to. They cannot be trusted. For all we know, he's here to scout out the College. I'm sure they want to undermine our efforts."
- What efforts would they be undermining? "This! This... Orb. The Eye of Magnus, whatever you want to call it. It's clearly powerful, and no doubt they want it for themselves! I expect to be informed if they make any future attempts to contact you."
- Have you ever heard of the Augur of Dunlain? "The what? No. No, I'm quite sure I have no idea what you're talking about. I suggest you mind your own business and return to whatever it is you do here."
- "I have many important things on my mind. Your concerns are not among them."
- "Are you quite sure we need to be speaking?"
- "I'm disappointed to say I've learned little during my time here."
- "I had hoped your scholars would be on a level comparable with my own colleagues. They are not."
- "Another new Apprentice, I see. Are you here because you believe you can change the world? Or are you only in it for yourself? I assure you I will be watching you - all of you - very closely."
- "You've come for me, have you? You think I don't know what you're up to? You think I can't destroy you? The power to unmake the world at my fingertips, and you think you can do anything about it?" ―During The Eye of Magnus
Mirabelle: "I believe I made myself rather clear."
Ancano: "Yes, of course. I'm simply trying to understand the reasoning behind the decision."
Mirabelle: "You may be used to the Empire bowing to your every whim, but you will find the Thalmor find no such treatment here. You are here at the pleasure of the Arch-Mage. I hope you appreciate the opportunity."
Ancano: "Yes, of course. The Arch-Mage has my thanks."
Mirabelle: "Very good. Then we're done here."
Mirabelle: "I've had yet another complaint. Please stop barging in on experiments in progress."
Ancano: "My dear, I am merely observing the proceedings."
Mirabelle: "Well then 'observe' from a greater distance. You're making people uncomfortable."
Savos: "I'm sorry, were you about to say something?"
Ancano: "Well, what is the meaning of this?"
Quaranir: "I'm sorry, I'm afraid I don't understand."
Ancano: "Don't play coy. You asked to see a specific member of the College. Here he/she is. Now what is it that you want?"
Quaranir: "There's been a misunderstanding. Clearly I should not be here. I shall simply take my leave."
Ancano: "What? What trickery is this? You're not going anywhere until I find out what you're up to."
Quaranir: "I'm not 'up to' anything. I apologize if I have offended you in any way."
Ancano: "We shall see about this..."
Ancano: "I'm afraid I must intrude. I need to speak to your associate immediately."
Tolfdir: "This is most inappropriate! We are involved in serious research here!"
Ancano: "Yes, I've no doubt of its gravity. This, however, is a matter that cannot wait."
Tolfdir: "Well, I'm quite sure I've never been interrupted like this before...the audacity!...[to player] I suppose we'll have to continue this at some later time, when we can avoid interruptions."
Ancano: "You've come for me, have you? You think I don't know what you're up to? You think I can't destroy you? The power to unmake the world at my fingertips, and you think you can do anything about it?"
Tolfdir: "Spells have no effect!"
Ancano: "I am beyond your pathetic attempts at magic. You cannot touch me."
Tolfdir: "The staff! Use it on the Eye!"
Ancano: "Enough! Still you persist? Very well. Come then. See what I can do now."
- Ancano is flagged as an essential character until the "Eye of Magnus."
- Ancano's corpse can be controlled by using Dead Thrall or The Ritual Stone.
- If Ancano is revived with Dead Thrall or the Ritual Stone power, he is one of the few characters that still speaks as if he were still alive. He will say things like "Who's there?" upon entering combat, and "That will teach you to cross me." when exiting it.
- Although she dislikes him, Nirya says she finds him "rather handsome."
- He and Elenwen are known to be the only Thalmor that wear/possess the non-hooded Thalmor Robes.
- Despite the fact that Ancano is an essential character, he can be attacked and, "killed," without any bounty or hostility from any surrounding people.
- Ancano may not become hostile when attacked by the Dragonborn, even when they are in their werewolf form.
- If Lydia is dismissed while Ancano is near, she may attack him and most likely be killed. This may also apply to other followers.
- When Ancano is using sparks on the Eye of Magnus, it will deal no damage when in front of it, and Wards will have no effect on it.
- Ancano is voiced by Alexander Brandon, who voices only one other character in Skyrim, Amaund Motierre.
- If Ancano is spoken to after conversing with Quaranir during, "Good Intentions," he will confess his fears that the Psijic Order, "wants the Eye for themselves," and demands that the Dragonborn informs him if the Psijic Order attempts to contact them again, though it is not possible to do so.
- If asked where the Augur of Dunlain is located during, "Good Intentions," Ancano will look worried and stutter that he has no idea what the Dragonborn is talking about, before telling them to go about whatever tasks that they normally do. It is revealed by the Augur that Ancano had been there before the Dragonborn, but asked questions of a different angle.
- When conversing with Ancano, there is an option to ask, "Who are the Thalmor?" However, if one has already spoken to other agents—random Thalmor Justiciars, Ondolemar in the Understone Keep, etc.—about the Thalmor, Ancano's dialogue option changes to, "I'd like to know more about the Thalmor."
- If one leaves the College before speaking to Urag gro-Shub during the beginning of Hitting the Books (searching for the staff for Onmund's Request, etc.), Faralda will approach the Dragonborn when they return and state that Ancano was looking for them, and she will mention that there are rumors circulating the College that Ancano is not an advisor but a spy for the Thalmor. He can be asked about this after meeting with Quaranir, where he will get extremely angry and reiterate that he is, "only an advisor," and firmly stating that the Dragonborn should not continue to spread this rumor about him around the College.