Commerce Road was an Imperial-built road in Black Marsh, the province of which the Argonians were native. It was poor quality road and was covered in reeds that always grew back onto the road despite numerous efforts to get rid of them including using fire and horses. It was used by merchants to ferry passengers and trade goods between the town of Slough Point and Hixinoag to the north and the city of Gideon to the south. Due to it being a major route of goods and passengers, it was often the site of raids by the Naga, a breed of Argonians who were considered responsible for a majority of the crime in Black Marsh.
Later, at the request of Ambassador Tseeixth, the Septim Empire placed magically-lit lanterns at regular intervals alongside the road, and built more Imperial Legion patrol stations to better secure the road from wild creatures and the Naga.