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While in search of a cure for lycanthropy, a witch in the guise of a raven, Ettiene of Glenmoril Wyrd, instructs the Nerevarine to retrieve the Heart of an Innocent. The Nerevarine must kill a female Nord, who Ettiene refers to as a "sacrificial lamb," at the Altar of Thrond to obtain it for a ritual.
- This ingredient has the same alchemical properties as a Daedra's Heart.
- Blood of an Innocent was originally intended to be used for the ritual, but was replaced by Heart of an Innocent.