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Sheogorath sent the Hero to speak to Lord Thadon, Duke of Mania, as part of the quest "Understanding Madness". Thadon will talk about the Chalice of Reversal, a cup that turns felldew into an intoxicant. He's not entirely clear on the details, but thinks that one of his people or Lady Syl, the Duchess of Dementia, has more information.