She is the final target of the side quests provided by Nazir in the Dark Brotherhood. After being given the contract, she will be able to tell the Dragonborn is an assassin and will be hostile immediately after dialogue ends.
"Let me guess - you have some "business" to discuss..."
- I represent the Dark... "The Dark Brotherhood? Yeah, yeah, yeah. You think this is the first contract I've had on my life? I'm a pirate, sweetie. Assassination attempts are an occupational hazard. Now, shall we?"
- You face the Dread Lord... "Sithis? Let me guess: "In the Void!" By the gods, you Dark Brotherhood are a predictable lot, aren't you? Okay, here's how this works. You try to assassinate me, and I kill you. Horribly. I have done this dance before, you know."
- (Remain Silent) "Ah, I see. The old Dark Brotherhood "silent intimidation" treatment. Oh, I know who you are. Don't be so surprised. You ain't the first assassin sent to kill me. Won't be the last. Now let's get this over with."