The card can be acquired by completing the main story of The Fall of the Dark Brotherhood.
- Using this card early is paramount. Destroying 20 creatures is very difficult, and takes time. One upside is that every turn, you may summon an enemy target that is +0/+1, which can easily be dealt with. Enemy cards are counted for every card that is destroyed, including ones that attack friendly creatures and die. When the 20th creature is killed, the opponent loses 20 health, you gain 20 health, and are rewarded up to 10 cards. The max cards that anyone can have in their hand at one time is 10.
- The Night Mother works great in combination with one, or several, Brotherhood Sanctuaries in play, combined with any creature holding the Slay ability. If used in combination with Lucien Lachance and a card such as Stalking Shadowscale, the 0/1 guard that the Night Mother can spawn can greatly increase the strength of Stalking Shadowscale. In an ideal scenario in which all three Brotherhood Sanctuaries are in play alongside Lucien Lachance, Stalking Shadowscale can turn from a 3/4 card to a 12/13 card in one kill. Another card to use instead of Stalking Shadowscale is a card with drain, such as Volkihar Lord. In the ideal scenario, Volkihar Lord can turn from a 7/7 card to a 13/13 card in one kill.
- Upon dealing 20 damage with this support, the player is awarded the title "The Lucky Lady."