Sure there's been plenty of talk regarding DLCs and all and the majority of readers probably don't care about this post but concerning large-scale downloadable content, what would you like to see? When I mean large-scale, I mean story-wise or simply DLC on a massive scale, not gameplay content.
Personally, I would love to have a Vigilant of Stendarr questline. Imagine having an Oblivion-esque storyline, visiting other realms of Oblivion and battling varieties of Daedra and perhaps even encounter Jyggalag. I wouldn't mind having Morrowind or Cyrodiil expansion but a few new questlines would be enough for me (even though I would lose my social life to Skyrim if a Morrowind and Cyrodiil expansion was released).